Tuesday, August 18, 2009

The Advantage of an Office Door: A Work Up for a Carb Up

Ever stolen a work out during the day, or snuck one in? Do you have to go to the gym to do it? At work, i have the privilege of an office with a door on it such that when it's shut, no one can see in, except the workers in the building going up right across from me. We wave at each other from time to time. when they're way hi up on their lego like structures. But now since they're all off for lunch, it is fine and proper to change my shirt and shorts for sweatable attire and commence a pre-lunch ritual: the carb burn pre load work up.


Yes work up: i am working up to a happy feeding time, knowing i'm not just eating cuz i'm a bit peckish; i'm refurbishing my muscles glycogen stores when they'll be happiest to receive them.

To achieve this today, i decide to do a 15:15 vo2max workout as per Viking Warrior Conditioning (reviewed here).

But then, mid workout, what happens? i start to feel a callus go - for those of you who do this kind of thing you know what i mean. I don't want a tear - i'm about to go away on a break and while i suppose that would be the ideal time to have a tear (if one must) i think i'd rather not. Band aids etc, no fun. Phooey.

So i do the a-typical smart thing and stop my vo2max work with a 12kg and transition gracefully into an on-the-fly adapted 8on 12 off session of swings for the next 11 minutes with a 24kg. Perfect form, perfect form. Every rep a perfect rep. My word, 12 secs post kettlebell seems much shorter post a kettlebell set than it does on the bike.

This protocol is based on one developed by Trapp and co for eliciting optimal fat burn in women of both athletic and not so athletic backgrounds. 20mins of 8/12 intervals seemed to be a sweet spot for fat burning.

1: Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2370-5. Epub 2007 Sep 26.Click here to read Links

Metabolic response of trained and untrained women during high-intensity intermittent cycle exercise.

School of Medical Sciences, Faculty of Medicine, Univ. of New South Wales, Sydney 2052, Australia. e.trapp@unsw.edu.au

The metabolic response to two different forms of high-intensity intermittent cycle exercise was investigated in young women. Subjects (8 trained and 8 untrained) performed two bouts of high-intensity intermittent exercise: short sprint (SS) (8-s sprint, 12-s recovery) and long sprint (LS) (24-s sprint, 36-s recovery) for 20 min on two separate occasions. Both workload and oxygen uptake were greater in the trained subjects but were not significantly different for SS and LS. Plasma glycerol concentrations significantly increased during exercise. Lactate concentrations rose over the 20 min and were higher for the trained women. Catecholamine concentration was also higher postexercise compared with preexercise for both groups. Both SS and LS produced similar metabolic response although both lactate and catecholamines were higher after the 24-s sprint. In conclusion, these results show that high-intensity intermittent exercise resulted in significant elevations in catecholamines that appear to be related to increased venous glycerol concentrations. The trained compared with the untrained women tended to show an earlier increase in plasma glycerol concentrations during high-intensity exercise.


As for the application of the above with a heavy kb, i can say after the 11th minute, it seems i may have found a way to test for a new max heart rate. Cuz that was higher than on a bike and not maximal. I was still standing. Hmm. On the fat loss, well i don't know. It's more effortful than on a bike. May try again with a 20kg, just to calibrate. Interesting enough to want to give it a go again.

Feeling very pleased to have done this work up.
Clean up; re-dress and regroup. Lunch becomes a happy happy thing. A definite re-fuel. Ideally if i'd been thinking straight i would have grabbed a lighter bell just to do some more cool down swings to get a bit more fat flamed off before it re-esterfies from sitting down again.

So what's the take away here:
  • glad i've FINALLY gotten to a place where i can change an envisioned workout in order to keep working out, rather than obsessively have to stick with ONE routine because, who's keeping track again? oh? just me? right-o.
  • doing short intervals with a heavy kb is an intriguing workout from both a cardiac and potential fuel burning perspective.
  • remember to stash chalk at work, too: a few more minutes and that 24 would have been sailing out of the office towards the new building. Even though that's rather a pleasant thought - sort of like shooting a canon at an enemy battlement, the consequences would not be pretty.
  • the snatch grip to avoid calluses in fast repeats is a skill to be learned - still
But i guess the biggie here is to suggest, i hope, that if you have the luxury of an office where you can close a door, or even not, one where you can safely swing a kettlebell, it's a great way to have a pre-lunch work-up.

If you'd like more info on feeding up and why post workout, and what that has to do with muscles, here' a bit more in a review i did of precision nutrition's individualization/carb tolerance.

Now for the post happy lunch cup of tea...

Monday, August 17, 2009

b2d readers request: blog features update - your experience/thoughts?

Dear b2d readers,

Hello and thanks as always for reading.

I've recently added a few new features to Begin to Dig and would like to
  1. let you know about them
  2. get your thoughts about them (if you care to share).
Search by Google. First is that google (who own blogger, the software for this blog) now make search in the blog available. It's close to the top on the right. What's really cool (i think) about this new search feature is that if you put in keywords, you get the list of matching articles right at the top of the blog. Cool. And there are category tabs too for even more refined results.

Have you tried this yet? would you? or you don't tend to poke around a blog to look for previous posts?

Related Reading List. Inspired by Chris over at conditioningresearch.blogspot.com, i've added a reading list that features some of the articles i've found that are cool and relate to b2d.

Do you check out any of the articles in the list? Do you come to the site ever to see what's on it?

Twitter Feed. I suppose this is the one i'm most dubious about. but i'm pretty new to the experience so keen to take advice.


(Not so new) Promoted free stuff and cool stuff. This isn't a new thing, but i'd like to hear your experiences here.

Not sure if folks who drop by check out the stuff that i review and put in the review area or put in the "freebies" area . I try not to put anything up that doesn't have a review associated with it, and nothing goes up that's not stuff i use, too. But not sure if really readers have the time to whiz through any of these - if you find them helpful.

(Not so new) Articles Listing. Related to the above, i keep articles on the right from stuff in b2d that may be useful for reference. Is this useful? Do you ever go to the article listing to re-find something you've seen? or to find something new, of interest?

Thanks for your time.
That's about it, i think. Keen to hear your thoughts, and very much appreciate you taking time from your day to let me know. Again, really value your spending some of your time at b2d. Thanks for digging, grokking, subscribing or just dropping by.

one announcement: for folks in the UK area, i'm doing a first UK public workshop blending z-health practice and theory with kettlebells. It's Sunday Oct 18, 9:30-4. There's a pretty good description of the workshop at the host's, LKB. Perhaps meet some of you there?

Thanks again,

mc

Lance Armstrong Training: almost with a kettlebell

Well, the image in men's fitness made famous of Lance Armstrong swinging a kettlebell may not have been repeated elsewhere, but one could believe he does swing, based on the following workout sample on youtube.

It starts with dynamic movement of weight - sorta like a swing.

Solid: weighted step ups, stable rows (i like rows:details here), and my faves in this example, weighted adductor lunges, starting everything off with these nice effortful hang cleans.

There's a kb hiding in a corner somewhere.

Sunday, August 16, 2009

Review of Kenneth Jay's Viking Warrior Conditioning for Proper VO2max training

This post is a review of Kenneth Jay's Viking Warrior Conditioning (VWC) for "proper VO2max training" . The review goes over the book and includes notes from an interview with Kenneth Jay on some of the finer details behind the VO2max and lactic acid pushing protocols of Viking Warrior conditioning.

o Cut to the Chase overview/recommendation:
If you are an athlete who needs stamina, strenght and endurance - whether on the field or in the gym; in team or in solo sports, this is an excellent protocol for maximally efficient cardiovascular conditioning.
A few quick reasons:
  • it's efficient, making good use of what we know about interval-based training
  • it works the whole body
  • it uses one relatively inexpensive piece of equipment that can be used pretty much anywhere one has room to swing a cat
  • the book itself has sufficient explanations for someone to understand why they need to do what's prescribed as prescribed, and it provides case studies and real people reports to show how this protocol works for real people.
  • It's a complete package.
Kenneth Jay, by the way, is a Master RKC and is both a coach of university teams, and world record holding athletes. It is also a pleasure to watch Kenneth Jay shop for his lunch.


o What's in this Review
The following review goes over who Viking warrior conditioning is for, how the book is presented, why the protocols presented are effective, how that's demonstrated, and why this book would be a great asset for strength and conditioning coaches, team coaches and athletes across the sports board, from cyclists to power lifters.

Who's this book for? Anyone who needs strength, stamina and power. Despite the fact that this book focuses on the use of the kettlebell snatch for its protocols, this book is not just for people devoted to the kettlebell. The kettlebell, and in this case, the single move the kettlebell snatch, just happens to be terrific for cardiovascular (CV) conditioning.

If you're an athlete who needs strength to move, stamina to keep moving and power to move something as effectively as possible, VO2max conditioning is a good idea.

Consider an athlete on a team where the team can go and go with skill and strength - right until about the last crucial ten minutes of the match. It's those last ten minutes that may just make the difference between having the concentration and energy to win against the other team.

Remember Andy Rodick at the end of this year's Wimbleton? Neck and neck with Federer till the last few minutes. Was it talent and skill or more energy reserves at that point that put Federer ahead of such a tight battle?

And what about just having the energy to get through a long day, whether that day is moving furniture or working out details of a troublesome project. Enhancing our capacity to move oxygen through our blood stream, improving its efficiency at doing so, and being able to work harder, longer for effectively less effort are all great things. These effects are great in an of themselves, plus they have super side benefits for health, longevity and well being.

o Caveat Before Starting
The only thing VWC assumes is that you already have some level of conditioning. That is, this is not a protocol for someone who is going from complete sedentary level to VO2 conditioning. Why?

Snatch Speed. The protocols in this book demand both skill with the kettlebell snatch in order to maintain perfect form with the KB when moving it quickly and repeatedly in both the down strokes (overspeed eccentrics) and the up strokes (explosive force).
Interval Effort. As Lyle McDonald summarized in an overview of the role of intervals in fitness, they're best suited to someone who has some base level fitness already. If just starting a fitness program, get used to moving first. And if you'd like to start moving with a kettlebell, excellent idea. I'd strongly encourage you to consider Enter the Kettlebell (reviewed here) for fitness, and Precision Nutrition (reviewed here) as a great habit building approach to nutrition.

o The Organization of VWC - a book in 4 main movements
Before getting into a discussion of Kenneth Jay's protocols, it's worth considering what else is in the book. The book is presented as 10 chapters. That may sound like a lot, but some of the chapters are quite succinct, and they fit into what might be described as three related movements:
  • First movement: the motivation for and explanation of how VO2max conditioning Works
  • Second movement: the protocols
  • Third movement: the case study: the protocols applied
  • fourth movement: testimonials of experiences with the VO2max protocol
o First Movement: Motivation and How VO2max Works

The initial sections build up why working on VO2max conditioning is an important and effective component in overall strength and conditioning work. An overview of the viking warrior conditioning concept is presented, and followed by an overview of cardiovascular physiology - no mean feat - followed by a discussion of force, finished up with a few thoughts on how the kettlebell - in particular the kettlebell snatch - ties all these attributes together.

Essentially, fast snatching with perfect form enables one to develop two properties of the heart: eccentric hypertrophy - its elasticity to pump lots of blood - and concentric hypertrophy - some thickening of the walls of the heart to handle the pressure of heavy loads for powerful efforts.

Oxygen is critical to our survival. Blood carries oxygen to our muscles; the effort of muscles uses up that oxygen and needs to be replaced. The effectiveness with which fresh blood can be powered through our veins is related to how effectively our heart can pump: how strong the force it can genearte (and sustain) and how much of the blood it can take in, it can actually get out of the heart again. (For more detail, Related discussion on cardio, kb's and energy system integration here)

What these combined actions of pumping blood out of the heart and getting it into the hungry muscles, mean is that the heart can get more oxygen both into and out of the muscles faster and more efficiently, and it can get more blood especially out of the heart with each beat. Better blood flow, and more O2 reaching the muscles combines to mean less fatigue and more power, stamina and, effectively strength.

Two Strengths of the Heart. Usually, endurance athletics like running or swimming or cycling develop eccentric hypertrophy, while resistance training and sprinting develop more concentric hypertrophy. It's important to develop both. And Kenneth's snatch protocol attests to doing both.

There's only really one other activity beside the kb snatch it seems that has been shown to simulate this simultaneous double effect on the heart, and that's rowing. And if you're Stuart McGill, you're not crazy about rowing because your back is in flexion a great deal of the time. This is not the case with the snatch.

Jay goes into some detail on how the cardiovascular system of the heart and bloodflow works. Some folks may want to skip this part and get to the protocols, and that's fine: it's there for reference. But for those who do want to get at *why* the protocols that follow will enhance those two key components of cardiovascular strength, the explanations are very good. They make a few assumptions - for example the Krebs cycle is mentioned without explanation, and the roles of lactic acid and why we might want to push on that is also left more stated than explained. But there's sufficient information that is well-explained to get a handle on the process, and seek out other sources in an informed way if more info is sought.

+ Second Movement: The VWC protocols
Viking Warrior Conditioning presents 5 protocols for VO2max conditioning. Each are progressive and build upon the previous one.

36:36 The most discussed protocols in the RKC kettlebell scene is the protocol Kenneth Jay first introduced to the RKC II certification a couple years ago. The 36:36. Why 36 secs on/36 seconds off. Kenneth Jay explains this in the book as follows:

Thrity-Six seconds is 60% of 1 minute. Research has shown that doing intervals at 60% of the time spent at VO2max is far superior to 50% (the suggestion of 30-second sets) or 70% or even 40% and 80% when doing high volumne work (35 sets)
One may ask, how is 36:36 representative of 60%, when the interval is 1:1. Isn't that 50% of 1min 12 secs total for the set? Shouldn't it be 36:24?

And so i did ask Kenneth exactly this. To which he replies that the focus in not on the work to rest interval ratio, but on the max time for VO2max work in a minute:
First thing is to remember the 60% does NOT refer to W:R ratio or the protocol itself. the 60% is taken from the time spent at MVO2 during the cadence test. in order to elicit a MVO2 response several factors has to be present among others a gradual build up- henc the 5 min test. the 5th minute is all out which should be VO2max and in order to take the slow component of the VO2 kinetics into account a minimum of 1 minute has to be kept (this is necessary because the test estimates as opposed to direct meassurement) The 36:36 sec. protocol is therefore derived by saying that if we are working at VO2max levels for 1 min during the test and research show (like esfarjani & Laursen, 2007 ao) that interval duration should be 60% of the time you are able to keep your VO2max then I arrive at 36 sec. IF I had chosen to have the cadence test last 5 1/2 in. with the last 1 1/ min all out then the work interval duration would have to be 60% of 90 sec (54 sec.) this would have been just as accurate if it had not been for a serious drop in snatch performance after 1 min all out- this is based on no published observations during my study but if the protocol was meant for runnig it could have easily been done. prolonging the final all out time with snatches it a differnet animal and most people would get a worng result.

At this point the work duriation has been established (60% of 1 min of the cadence test) and since that equals 36 sec I decided the protocol should have a 1:1 W:R ratio. When the interval work duration is less that 1 min. this is advisable. also based on research (michalisk& Bangsbo) when the intervals gets longer- the rest also has to increase.

So in short. remember that the 60% is derived from the cadence test and nothing else!

Cool.
For backup to the above, Kenneth references the following article in particular:

J Sci Med Sport. 2007 Feb;10(1):27-35. Epub 2006 Jul 28.Click here to read Links
Manipulating high-intensity interval training: effects on VO2max, the lactate threshold and 3000 m running performance in moderately trained males.
Esfarjani F, Laursen PB.

School of Science and Physical Education, Esfahan University, Esfahan, Iran.

The aim of this study was to compare the effects of two high-intensity interval training (HIT) programmes on maximal oxygen uptake (.VO(2max)), the lactate threshold (LT) and 3000 m running performance in moderately trained male runners. .VO(2max), the running speed associated with .VO(2max) (V.VO(2max)), the time for which V.VO(2max) can be maintained (T(max)), the running speed at LT (v(LT)) and 3000 m running time (3000 mTT) were determined before and following three different training programmes performed for 10 weeks. Following the pre-test, 17 moderately trained male runners (V O(2max)=51.6+/-2.7ml kg(-1)min(-1)) were divided into training groups based on their 3000 mTT (Group 1, G(1), N=6, 8 x 60% of T(max) at V.VO(2max), 1:1 work:recovery ratio [that should look familiar -mc]; Group 2, G(2), N=6, 12 x 30s at 130% V.VO(2max), 4.5 min recovery; control group, G(CON), N=5, 60 min at 75% V.VO(2max)). G(1) and G(2) performed two HIT sessions and two 60 min recovery run sessions (75% V.VO(2max)) each week. Control subjects performed four 60 min recovery run sessions (75% V.VO(2max)) each week. In G(1), significant improvements (p<0 .05=".05" p="0.07)." style="color: #663300;">HIT programmes in moderately trained runners, but that changes in performance and physiological variables may be more profound using prolonged HIT at intensities of V.VO(2max) with interval durations of 60% T(max).
It's also cool to note that the above study is based on "moderately" trained runners - so not super jocks. And since this is the level - moderately trained - of where most folks will begin with the VO2max protocol, then there's good reason to use the optimal protocol for this approach in the vo2max effort.

The other Protocols. Beyond 36:36 there is one preliminary/prepatory protocol before diving into 36:36, and then three other peaking and pushing protocols that focus on both pushing beyong VO2max and on lactic acid tolerance.

Indeed lactic acid is in the title of the three post 36:36 protocols, and its one concept that Viking Warrior Conditioning does not directly explicate. So i asked Kenneth if he could talk about that focus a bit more here. Here's what he said:
Basically production and tolerence of lactic acid is a great indicator of how well your anaerobic system is conditioned. A high production rate means that ATP is synthesized very quickly and a high tolerence rate means that just that- you can continue to work in a very acidic environment.
(For a quick overview of ATP, what it is, and why it's important, take a look at the middle-ish of this post on fat-as-fuel.)

Likewise, what about going over VO2max? How can we do something at MORE than 100%? If that more than 100% feels like Spinal Tap's amplifier ("it goes to 11"), then a couple things to remember. First we have more than one energy system we can draw on, each being categorized as aerobic (using oxygen) and anaerobic (not using oxygen). When the aerobic capacity gets tapped out - or we hold our breath for an intense effort - we're drawing on those anaerobic energy levels. I asked KJ if he could describe this beyond 100% V02max capacity, and he came back with the following analogies:
[Going over 100% is possible becuase] the body basically has two ways to make energy: those are aerobic and anaerobic. Aerobic means "with oxygen" and anaerobic means "without oxygen" VO2 is the most acurate way to express how much the AEROBIC system is taxed.

When we reach 100% MVO2 we cant get more out of the aerobic system BUT we still have the ANAEROBIC system to push harder. Going above 100%MVO2 just means that you are doing something faster than what your aerobic system can handle alone.

Think about it is way: Ever seen the movie "the Fast and the Furious"? The guys in the film fine tune their cars to the limit. putting in all the right parts- the lightest, most durable stuff, the best turbos etc. that is the equivalent of the VO2max. The cars probably max out at a top speed of 160-170 mph (which we will call 100%) or something like that. BUT then they have the NOS. that injection will make the cars go close to 200 mph or +100%. The NOS = the anaerobic system. Of course that is a very simplified way of looking at it but it gets the idea through. (hopefully)
Going over 100% VO2max also pushed lactic acid production at a faster rate than a lower rate. So the two effects are strongly related.

How Long to Do Them All? Kenneth Jay's protocols, informed by recent research on best-tapping of energy production and tolerances for optimal work. If a person has the stamina to move through each protocol in succession, it will take approximately 30 -36weeks - in other words the better part of a year.

Of course, these protocols are the crown jewels of the book, but as a good coach, Kenneth doesn't simply say here's a bunch of nifty protocols; he provides a few contexts in how they can be applied. Thus the next sections of Viking Warrior Conditioning present how to put these strategies to work.


o Third Movement: Thorolf and Friends
The Protocol section closes with three strategies of how VWC might be adapted to co-exist within anyone's current training practice. This also includes KJ's own prefered approach. But the part of the book that is a particular asset is the case study that follows.

Here we see charted out exactly how one "moderately trained" 35 year old male, Throlof, did following the first four of the five Viking Warrior Conditioning protocols. Each protocol is mapped out on a per session /per week basis to see progression of volume.

We see the calculations for percentage over VO2max worked out to go with particular protocols. The only thing we do not see is Thorlof hooked up to a cart to validate that the calculated VO2max percentatges are validated in practice. Given that these calculations however are based on a lot of research that has been tested, and since we can see Thorlof's progress we can be pretty confident there is a strong progressive effect.

Kenneth Jay also stated in our exchanges that yes Thorolf really exists and yes these are his numbers.

Active Rest. Something also keen to note in the case study are the back off weeks in the program. Either Thorolf has great instincts or a great coach, but he kept himself sane by backing off for a bit and coming back stronger than before for a persistent, consistent linear progression of results over time.

Intervals vs other CV conditioning. Kenneth rounds off the Thorolf section with a nice discussion of the benefit of interval training vs. steady state. This chapter has the unfortunate title of "why the fat burning zone is a joke" but aside from that he makes the now well established case that in 2/3's the time of a steady state 75% Max heart Rate workout one is burning significantly more calories, and hence getting at more fat - so getting lean is good. The section also touches on why intervals like these have other benefits than steady state - and that may be the key thing, more than how many calories are burned or not.

What we know from increasing amounts of data is that, at a certain intensity of effort, things start happening at the DNA level of our responses to demands for fuel that have effects not just on our hearts but on our muscels, too. We touched on this a couple of weeks ago in this research review of the 6mins in 2weeks Efforts and its potential applications.

To complete the discussion on the benefits of Viking Warrior Condition, Kenneth concludes with a discussion on Conditioning and on Power, how they relate and how, not surprisingly, VWC helps develop each of the areas discussed. The discussion on general conditioning is particularly strong, discussing fatigue management, its relation to work capacity and the role of oxygen uptake - the latter being a big chunk of what VO2max work is about.

o Fourth Movement: Real People - well, RKC's and a Fighter- using VWC
What comes as a surprise in the book is the chapter that simply presents 3 RKC's of varrying levels writing about their experience with the VWC protocols. 2 of the 3 writers is a woman. That's cool. It's difficult in reading through these experiences not to see how they might be applicable to a range of athletes. To drive the point home, the section concludes with an interview of Mark O Madsen (also an RKC) who is a "world ranked Greco-Roman wrestler." The core take away from this interview is that the kettlebell is one of many tools the athlete uses regularly, with the 15:15 protocol being his main VWC protocol - from which he's getting a lot of mileage. The take home is this is a serious athlete "ranked 2nd in the world" - so if this approach wasn't working for him in a serious way, it would not be in his training.

o Coda
The book finishes with a review of the RKC hardstyle snatch. In an interview with Geoff Neupert, Kenneth Jay reiterated that he takes as a base level for this protocol someone who has gone through Pavel Tsatsouline's Enter the Kettlebell Program Minimum and Rite of Passage protocols for basic level comfort and control in kettlebell work.

Since this is such a snatch heavy program, seeing an RKC trainer to check snatch form is a Good Idea, too.

Kenneth in his Call to Action promises that Viking Warrior Condition will offer a transformative experience of conditioning like no other. After reading the book, you'll know not only how to make that happen but why these protocols will deliver that. And based on the the testimony of the people in the book, there's excellent support to show that the claims are not unwarranted.

A word for Rif. One other voice prefaces the book, Master RKC Mark Reifkind. He has not only written about his experience in the book's forward, but he's chronicled it as well on Rif's blog. His and Tracy Reifkind's progress with these protocols is perhaps kenneth's best testament to their efficacy. Every claim Rif makes in the forward is documented - frequently with video - for all to see.

o Other Athletes: Runners And Rugby Forwards.
Something i've started to investigate with some athletes is how VWC might be interleaved with their running practice to reduce hard miles on their bodies and up their performance. It's early days, but this has promise.

Another place some of us will be looking at in the fall is how VWC can improve the end-of-game stamina of a team's rugby forwards - complementing, not interupting, their pre and in-season training.

o Summary
VIking Warrior Condition is an intense program that promises to deliver persistent, consistent results.

The book may feel thin in the hands at 109 pages, but as such it's also a highly practical, efficient manual that anyone can wrap their heads around in a single sitting, and come back to as necessary when moving up the protocols.

If you're interested in tested practical applications of interval training for cardiovascular fitness, strength and stamina, for excellent conditioning, and would like to use a simple implement to achieve these ends, this is a book worth having, and approach worth practicing.

Let me know how go your results.


Kenneth Jay's Viking Warrior Conditioning, published by Dragon Door, 2008.

Related recommended resources
Enter the Kettlebell
Precision Nutrition
Kettlebells:
In the US: dragondoor kettlebells
In the UK: kettelbell Fever


Related Posts

Friday, August 14, 2009

Brown Fat: New Improved Single Factor Thinking

Let me predict it here first, folks: Brown Fat will be the Next Big Thing in the Drive for a Single Factor Big Pill Solution to Obesity.

Put "brown fat" into google today and you'll see all sorts of clever people and magazines referencing this new study on how "brown fat" (used a lot for generating body heat in mamals and neonatals) can be used to help burn the evil "white fat" - our abundant adipose tissue.

Yes evil, says the article, in contrast to the "good fat" story from early last week i was telling. The article commences powerfully:
IN THE war on our waistlines, fat is the enemy. It is fat, or adipose tissue, that gives us our beer bellies and our love handles, our man boobs and our muffin tops. And when plastic surgeons sculpt people into slenderness, it is fat tissue they suck up and throw out with the clinical waste.

Electron micrographs of brown fat cells reveal one of their hallmarks: an extraordinary number of mitochondria, which, as described below, are involved in heat generation.
The mitochonria are typically round, with cristae across their entire width.

My favorite quote by one of the researchers from this story exemplifies single factor thinking:

"I exercise on an elliptical trainer and it's pretty hard for me to burn up 500 calories," says Ronald Kahn, head of obesity research at Harvard Medical School's Joslin Diabetes Center. "If I could do it without working and do it every day, it would be pretty great."
Wow, where to begin here? Nigh on 20 years back there was a furor that was kicked off with Matel's "Math is hard" Barbie. What that was saying to kids - young girls especially?

Here, we have a head of a medical group, reminiscent of Barbie, saying gee, working out every day is hard; wouldn't it be great if i had a pill to lose weight for me?"

THis is the height of medical research? Wouldn't it be great to have a pill? Maybe that is the height of medical research: it's not about health, well being, quality of life, but about how far can we push this single thing for that effect.

If medicine were about well being perhaps the kinds of questions it would ask would be What are the issues around such weight gain? how does behaviour (neurology) interact with physical being (physiology)? what's the forensic differences between the Lean minority and the increasingly Fat majority? whether lean or fat what are the complex beneficial interactions of eating and movement and rest/sleep on a whole range of homeostatic factors that impact well being? do they have even greater impact on any level for those who are obese? doing things like improving insulin sensitivity, bone mineral density, cardio vascular fitness, ant-aging, balance, vision, awareness, focus? Knowing these complex interplays of systems to create a myriad of positive effects, is another drug or surgical intervention a good idea?

No? so what's on offer? A pill? and if not a pill how about an invasive procedure?
Researchers are experimenting with various ways to increase the amount or activity of our brown fat, either pharmaceutically or even surgically, by extracting ordinary white fat through liposuction, transforming it into brown fat and re-implanting it. A mere 50 grams of brown fat - well within the range of what some of us already have - could dissipate around 500 calories a day
and why is this single factor thinking?

It's single factor thinking because it gets excited about saying "gee, if we could just tweak this one thing, wouldn't that be great if life were that simple...ok there may be side effects but look at that fat go...ok maybe nothing's happening with bone mineral density or strength, but look at that fat go." And some side effects like anti-anti-aging, are acknowledged:

Manipulating brown fat, whether by drugs or surgery, may not be risk-free, however. By increasing energy expenditure you generate a high-flux metabolic state, points out Celi. This could increase our exposure to potentially harmful free radicals generated by the metabolism, which could conceivably cause cancer or even hasten ageing.
But what if there's a reason that we have fewer brown fat cells as we age; maybe it helps us age better?

Enthusiasm for the potential is unquenched. Here's another quote from the same article:

Nedergaard believes the focus should be on preventing the decline in brown fat as people get older. "Most obesity appears in middle age and onwards, and this is when it seems brown fat activity starts to disappear," he says. It might be possible to identify the cause of this decline and then reverse it, perhaps by replacing a lost hormone. What this hormone might be, though, remains a mystery.

Right, well is that statement true? Increasingly, most obesity appears now in kids. The rate is growing almost exponentially, right? (remember the piece a few weeks about about resistance workouts and obese kids - and how they lost no adipose tissue?) and kids apparently have way more brown fat cells than middle age folks apparently. So, maybe obesity isn't age related, or about just brown fat cell ratios.

You know this may be exciting science and the source of many future publications and god knows how many dead rats in the process of Losing Weight, but it feels (a) arrogant and (b) taking the easy way out.

By analogy in Europe, there's laws against the sale of foods produced from GMO - genetically modified crops. Many farmers and People generally don't trust scientific manipulations in the food supply at such a vast level messing with what is perceived as Nature. There's concern that Something could go Horribly Wrong. To allude to another ancient trope for margarine commercials "It's not nice to fool Mother Nature"

Likewise the arrogance here is that we can find a Single Solution that will work in a Complex System (like us) and not think there'll be significant consequences. The taking the easy way out feels just ignorant. And in no small part disrespectful. We are complex organisms. Worse, we have psychologically reinforced habits wired up to physiological, homeostatically defined responses: we have behaviours wired into us for a non-fuel-abundant environment. And now we have abundant access to personal fuel. No wonder we're getting fatter.

Saying that, i'll say it again, it takes work and skills and practice and support to know how to change habits, to keep them changed and, initially, work against what are bodies are telling us to do: eat! The formula might be easy: eat less/move more, but the implementation is not simple, and sure as heck isn't saying gee let's just change this biological function. I bet that will be great! i won't have to work out. And we'll make lots of money to help other people not have to learn how to cook and move and learn habits of lean eating.

That sound cynical? Afterall these scientists are keen; they want to help solve an epidemic. And at least one of them is motivated to get off the eliptical. And i say Good For You - get off the elliptical and get something healthy like a kettlebell or a water rower.

But that's not what this anti exercise head of a diabetes research group is thinking - at least not as portrayed in this article. He thinks swap activity for pill. One Single Thing (workout: hard) for some Other Single Thing (pill: easy).

But we know that exercise is not a Single Thing - depending on how hard, how long, how frequently etc etc there are all sorts of effects going on inside that are good for us, hitting an abundance of systems: visual, vestibular, proprioceptive, mechanical, chemical, biological.

By comparison what does taking a pill do? We go from rich multi-factor interactions when we move to a far narrower set of internal interactions in ingesting a pill. And this from someone who should Know Better, don't you think?



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Thanks to Xafier for pointing out this article to me,
and let me cite Eric Cobb again for framing the notion of single factor thinking, covered in the 9S:sustenance cert.

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